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Glossary Term
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Hydrogen Peroxide Sterilization

Definition

Hydrogen peroxide sterilization, also known as vaporized hydrogen peroxide (VHP) sterilization, is a low-temperature sterilization method that uses hydrogen peroxide vapor to eliminate microorganisms, including bacteria, viruses, and spores, on medical devices and equipment. This process is highly effective for heat- and moisture-sensitive devices, offering a safe and efficient alternative to high-temperature or wet sterilization methods.

Relevance to the MedTech Industry

Hydrogen peroxide sterilization ensures that delicate medical devices are sterile and safe for use, particularly those that cannot withstand the high temperatures of autoclaving or the residual toxicity of ethylene oxide (EtO) sterilization. It provides an efficient and environmentally friendly solution for sterilizing modern, sensitive medical technologies.

Additional Information & Related Terms

How It Works

  1. Introduction: Devices are placed in a sterilizer chamber, and liquid hydrogen peroxide is vaporized to create a sterilizing agent.

  2. Diffusion: The hydrogen peroxide vapor diffuses throughout the chamber, contacting all exposed surfaces of the devices.

  3. Microbial Kill: The vapor disrupts the cellular components of microorganisms, leading to their destruction.

  4. Aeration: The chamber removes residual hydrogen peroxide, ensuring devices are safe for use without harmful residues.

Device Types Suitable for Hydrogen Peroxide Sterilization

  • Heat- and Moisture-Sensitive Devices: Devices like endoscopes, cameras, and surgical instruments with electronic components.

  • Flexible Plastics: Items such as catheters and tubing that might degrade in high-temperature environments.

  • Multi-Channel Instruments: Devices with intricate designs, such as laparoscopic tools, that require thorough sterilant penetration.

Device Types Unsuitable for Hydrogen Peroxide Sterilization

  • Absorbent Materials: Materials like cellulose-based products, such as paper or cotton, can absorb hydrogen peroxide, reducing its efficacy.

  • Liquids: The process is not suitable for sterilizing liquids or items containing liquids.

  • Metal Items Prone to Corrosion: Certain types of metals may degrade when exposed to hydrogen peroxide over time.

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