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Glossary Term
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Microfluidics in Diagnostics

Definition

Microfluidics refers to the manipulation of small volumes of fluids—typically in the microliter to nanoliter range—within channels on a microscale platform. In diagnostics, microfluidic technologies enable precise analysis of biological samples, facilitating rapid, portable, and cost-effective testing for diseases and conditions.

Relevance to the MedTech Industry

Microfluidics revolutionizes diagnostics by miniaturizing laboratory processes, enabling faster and more efficient tests. These devices support point-of-care (POC) testing, early disease detection, and personalized medicine, improving healthcare access and outcomes.

Additional Information & Related Terms

Applications of Microfluidics in Diagnostics

  1. Point-of-Care Testing (POCT):

    • Portable devices for rapid diagnostics, such as glucose meters, COVID-19 tests, or pregnancy tests.

  2. Molecular Diagnostics:

    • Enabling PCR and next-generation sequencing on a microfluidic chip for detecting genetic markers of diseases.

  3. Immunoassays:

    • Detecting biomarkers for conditions like cardiac diseases, cancers, or infectious diseases.

  4. Cell Analysis:

    • Performing single-cell analysis, blood typing, or monitoring circulating tumor cells (CTCs) in oncology.

  5. Environmental and Pathogen Detection:

    • Testing for pathogens in food, water, or clinical samples with rapid, on-site microfluidic systems.



Related Terms

  • Lab-on-a-Chip (LoC): Microfluidic devices that integrate multiple laboratory functions onto a single platform.

  • Point-of-Care Testing (POCT): Diagnostic tests performed at or near the site of patient care.

  • Biomarkers: Biological molecules used as indicators of normal or pathological processes, often measured with microfluidics.

  • Molecular Diagnostics: Techniques to analyze genetic material, often enhanced by microfluidic technology.

  • Sample-to-Answer Systems: Fully automated platforms that take a biological sample and deliver diagnostic results.

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