Glossary Term
Bone Graft Substitute
Definition
A Bone Graft Substitute is a synthetic, biologic, or natural material used to replace or augment natural bone in orthopedic, dental, and spinal procedures. These substitutes facilitate bone regeneration by providing a scaffold for new bone growth, delivering bioactive agents, or stimulating cellular activity.
Relevance to the MedTech Industry
Bone Graft Substitutes are critical for treating bone defects resulting from trauma, disease, or surgery. They reduce the need for autografts (harvested bone from the patient), minimizing donor site morbidity and surgical complications while promoting effective healing and structural integrity.
Additional Information & Related Terms
Osteoconductivity The ability of a material to act as a scaffold for new bone growth.
Osteoinductivity The capability of a material to stimulate bone-forming cells to differentiate and regenerate bone tissue.
Biocompatibility/Biocompatibility Standards Ensures that the substitute is safe for implantation.
Autograft The gold standard for bone grafting that Bone Graft Substitutes aim to replace or supplement.