Glossary Term
Translational Research
Definition
Translational research refers to the process of applying findings from basic scientific research to develop new therapies, interventions, or medical devices that can be used to improve patient care and health outcomes. It bridges the gap between laboratory discoveries (basic research) and clinical applications (clinical research), often referred to as "bench to bedside" research. The goal of translational research is to expedite the process of bringing scientific discoveries from the research lab into practical, real-world applications that directly benefit patients.
Relevance to the MedTech Industry
Translational research accelerates the application of scientific knowledge to clinical practice, ensuring that innovations in medicine and healthcare are rapidly and effectively developed into tangible treatments or technologies. Translational research aims to make research findings more relevant to patient care by translating discoveries into actual treatments, diagnostics, or preventive measures that improve health.
Additional Information & Related Terms
Key Components of Translational Research
Bench-to-Bedside Approach:
The "bench-to-bedside" concept is central to translational research. It involves moving discoveries made in the laboratory (the "bench") into clinical settings (the "bedside") where they can directly benefit patients.
Collaboration Between Disciplines:
Translational research involves collaboration between basic scientists, clinicians, regulatory experts, and engineers. This interdisciplinary approach ensures that discoveries can be rapidly moved from the research stage to clinical applications.
Preclinical Studies:
Translational research often begins with preclinical studies, which involve laboratory and animal testing to assess the safety and effectiveness of a potential treatment or device before it is tested in humans.
Clinical Application and Testing:
Translational research emphasizes the rapid transition from laboratory or animal testing to clinical trials. The goal is to test new therapies, devices, or treatments in human populations as quickly and efficiently as possible.
Related Terms
Bench-to-Bedside: The concept of moving scientific discoveries from laboratory research (bench) to clinical practice (bedside) to benefit patients directly.
Clinical Trials: Controlled trials conducted to test the safety and efficacy of medical treatments, devices, or interventions, often involving translational research.
Preclinical Studies: Research conducted in laboratories or animal models before clinical trials, used to assess the safety and effectiveness of new treatments or devices.
Regulatory Approval: The process by which regulatory bodies, such as the FDA, review clinical trial data and grant approval for new drugs or devices to be marketed to the public.
Personalized Medicine: An approach to treatment and healthcare that uses information about a patient's genetic makeup and other factors to tailor therapies to their specific needs.